SLE Criteria/American College of Rheumatology 1982 revised criteria for lupus

12:34 PM No comments

Any 4 or more of the 11 criteria are required to classify a patient as having SLE. These criteria do not have to be present all at once.

Malar rash: Fixed erythema, flat, or raised, over the malar eminences, characteristic sparing of the nasolabial folds.

Discoid rash: Erythematous raised patches with adherent keratotic scaling with or without plugging of the follicles; scarring may occur in older lesions.

Photosensitivity

Oral ulcers: Usually painless, Have to be observed by physician. History of ulcers is not sufficient.

Arthritis: Usually nonerosive arthritis

Serositis(inflammation of visceral membranes): Pleuritis or Pericarditis.

Renal involement: Persistent proteinuria >0.5 g/day or >3+ if quantification not performed OR Cellular casts.

Brain involvement: Seizures OR Psychosis.

Hematologic disorder: Hemolytic anemia OR Leukopenia: <4000/mm^3 on ?2 occasions OR Lymphopenia: <1500/mm^3 on ?2 occasions OR Thrombocytopenia: <100,000/mm^3.

Immunologic disorder:
Anti-DNA antibody
Anti-Smith antibody
Antiphospholipid antibodies based on:
- increased level of IgG or IgM anticardiolipin antibodies
-positive lupus anticoagulant
-A false-positive serologic test for syphilis


Antinuclear antibody:
An abnormal titer of antinuclear antibody by immunofluorescence or an equivalent assay at any point in time and in the absence of drugs known to be associated with drug-induced lupus syndrome.

Posted in: MEDICAL,USMLE